Inhibition of PDE1-B by Vinpocetine Regulates Microglial Exosomes and Polarization Through Enhancing Autophagic Flux for Neuroprotection Against Ischemic Stroke

Exosomes contribute to cell–cell communications. Emerging evidence has shown that microglial exosomes may play crucial role in regulation of neuronal functions under ischemic conditions. However, the underlying mechanisms of microglia-derived exosome biosynthesis are largely unknown. Herein, we repo...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Zang, Jiankun, Wu, Yousheng, Su, Xuanlin, Zhang, Tianyuan, Tang, Xionglin, Ma, Dan, Li, Yufeng, Liu, Yanfang, Weng, Ze’an, Liu, Xuanzhuo, Tsang, Chi Kwan, Xu, Anding, Lu, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889976/
https://ncbi.nlm.nih.gov/pubmed/33614626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.616590
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