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Hypoxia Induced Ubc9 promoter hyper-methylation regulates IL-17 expression in ulcerative colitis
Dysregulated IL-17 expression is central to the pathogenesis of several inflammatory disorders including ulcerative colitis (UC). We have shown earlier that sumoylation of ROR-γt, the transcription factor for IL-17, regulates colonic inflammation. Here, we show that the expression of Ubc9, the E2 en...
Shranjeno v:
| izdano v: | J Immunol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7889719/ https://ncbi.nlm.nih.gov/pubmed/33504619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000015 |
| Oznake: |
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