Hemodynamic and transcriptomic studies suggest early left ventricular dysfunction in a preclinical model of severe mitral regurgitation

OBJECTIVE: Primary mitral regurgitation is a valvular lesion in which the left ventricular ejection fraction remains preserved for long periods, delaying a clinical trigger for mitral valve intervention. In this study, we sought to investigate whether adverse left ventricular remodeling occurs befor...

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Detalhes bibliográficos
Publicado no:J Thorac Cardiovasc Surg
Main Authors: Corporan, Daniella, Onohara, Daisuke, Amedi, Alan, Saadeh, Maher, Guyton, Robert A., Kumar, Sandeep, Padala, Muralidhar
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889661/
https://ncbi.nlm.nih.gov/pubmed/33277035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2020.08.119
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