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Inhibition of indoleamine 2,3-dioxygenase 1 synergizes with oxaliplatin for efficient colorectal cancer therapy

We investigated the immunogenic cell death provoked by oxaliplatin (OXA) and the involvement of OXA-induced immunosuppression in colorectal cancer. Immune-proficient or -deficient mice were employed to evaluate the therapeutic effects of OXA. Immunogenic cell death was characterized by cell-surface...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Miao, Xiaofei, Zhang, Ye, Li, Zengyao, Huang, Longchang, Xin, Taojian, Shen, Renhui, Wang, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889448/
https://ncbi.nlm.nih.gov/pubmed/33665222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.12.013
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