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Pirfenidone Alleviates Choroidal Neovascular Fibrosis through TGF-β/Smad Signaling Pathway

Background. Transforming growth factor-β (TGF-β) plays a major role in CNV. However, the mechanism is unclear. This study investigates the effect of Pirfenidone (PFD) on TGF-β/Smad signaling pathway on the development of choroidal neovascular fibrosis in choroidal neovascularization (CNV) mouse mode...

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Detalhes bibliográficos
Publicado no:J Ophthalmol
Main Authors: Gao, Chuang, Cao, Xin, Huang, Lili, Bao, Yueqi, Li, Tao, Di, Yue, Wu, Liucheng, Song, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889376/
https://ncbi.nlm.nih.gov/pubmed/33628482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8846708
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