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Microrheology reveals simultaneous cell-mediated matrix stiffening and fluidization that underlie breast cancer invasion

Living tissues embody a unique class of hybrid materials in which active and thermal forces are inextricably linked. Mechanical characterization of tissues demands descriptors that respect this hybrid nature. In this work, we develop a microrheology-based force spectrum analysis (FSA) technique to d...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Krajina, Brad A., LeSavage, Bauer L., Roth, Julien G., Zhu, Audrey W., Cai, Pamela C., Spakowitz, Andrew J., Heilshorn, Sarah C.
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7888921/
https://ncbi.nlm.nih.gov/pubmed/33597244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe1969
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