Reduced circulating dendritic cells in acute Plasmodium knowlesi and Plasmodium falciparum malaria despite elevated plasma Flt3 ligand levels

BACKGROUND: Plasmodium falciparum malaria increases plasma levels of the cytokine Fms-like tyrosine kinase 3 ligand (Flt3L), a haematopoietic factor associated with dendritic cell (DC) expansion. It is unknown if the zoonotic parasite Plasmodium knowlesi impacts Flt3L or DC in human malaria. This st...

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Bibliografski detalji
Izdano u:Malar J
Glavni autori: Loughland, Jessica R., Woodberry, Tonia, Oyong, Damian, Piera, Kim A., Amante, Fiona H., Barber, Bridget E., Grigg, Matthew J., William, Timothy, Engwerda, Christian R., Anstey, Nicholas M., McCarthy, James S., Boyle, Michelle J., Minigo, Gabriela
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7888183/
https://ncbi.nlm.nih.gov/pubmed/33593383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-021-03642-0
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