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Quantitative Systems Pharmacology Modeling of PBMC-Humanized Mouse to Facilitate Preclinical Immuno-oncology Drug Development

[Image: see text] Progress in immunotherapy has resulted in explosively increased new therapeutic interventions and they have shown promising results in the treatment of cancer. Animal testing is performed to provide preliminary efficacy and safety data for drugs under development prior to clinical...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Ma, Huilin, Pilvankar, Minu, Wang, Jun, Giragossian, Craig, Popel, Aleksander S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887858/
https://ncbi.nlm.nih.gov/pubmed/33615174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00178
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