Senescent Tumor Cells Build a Cytokine Shield in Colorectal Cancer

Cellular senescence can either support or inhibit cancer progression. Here, it is shown that intratumoral infiltration of CD8(+) T cells is negatively associated with the proportion of senescent tumor cells in colorectal cancer (CRC). Gene expression analysis reveals increased expression of C‐X‐C mo...

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Veröffentlicht in:Adv Sci (Weinh)
Hauptverfasser: Choi, Yong Won, Kim, Young Hwa, Oh, Seung Yeop, Suh, Kwang Wook, Kim, Young‐Sam, Lee, Ga‐Yeon, Yoon, Jung Eun, Park, Soon Sang, Lee, Young‐Kyoung, Park, Yoo Jung, Kim, Hong Seok, Park, So Hyun, Kim, Jang‐Hee, Park, Tae Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887594/
https://ncbi.nlm.nih.gov/pubmed/33643790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202002497
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