ABCC6 deficiency promotes dyslipidemia and atherosclerosis

ABCC6 deficiency promotes ectopic calcification; however, circumstantial evidence suggested that ABCC6 may also influence atherosclerosis. The present study addressed the role of ABCC6 in atherosclerosis using Ldlr(−/−) mice and pseudoxanthoma elasticum (PXE) patients. Mice lacking the Abcc6 and Ldl...

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Publicado en:Sci Rep
Main Authors: Brampton, Christopher, Pomozi, Viola, Chen, Li-Hsieh, Apana, Ailea, McCurdy, Sara, Zoll, Janna, Boisvert, William A., Lambert, Gilles, Henrion, Daniel, Blanchard, Simon, Kuo, Sheree, Leftheriotis, Georges, Martin, Ludovic, Le Saux, Olivier
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887252/
https://ncbi.nlm.nih.gov/pubmed/33594095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82966-y
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