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Impact of Sequencing Depth and Library Preparation on Toxicological Interpretation of RNA-Seq Data in a “Three-Sample” Scenario

While RNA-sequencing (RNA-seq) has emerged as a standard approach in toxicogenomics, its full potential in gaining underlying toxicological mechanisms is still not clear when only three biological replicates are used. This “three-sample” study design is common in toxicological research, particularly...

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Publicat a:Chem Res Toxicol
Autors principals: Li, Dongying, Gong, Binsheng, Xu, Joshua, Ning, Baitang, Tong, Weida
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887111/
https://ncbi.nlm.nih.gov/pubmed/33354967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.0c00368
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