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The Promise and Peril of Population Genomics for the Development of Genome-first Approaches in Mendelian Cardiovascular Disease
The rich tradition of cardiovascular genomics has placed the field in prime position to extend our knowledge toward a genome-first approach to diagnosis and therapy. Population-scale genomic data has enabled exponential improvements in our ability to adjudicate variant pathogenicity based on allele...
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| Vydáno v: | Circ Genom Precis Med |
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| Hlavní autor: | |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7887109/ https://ncbi.nlm.nih.gov/pubmed/33517676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.120.002964 |
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