Molecular Imaging of Chimeric Antigen Receptor T Cells by ICOS-ImmunoPET

PURPOSE: Immunomonitoring of chimeric antigen receptor (CAR) T cells relies primarily on their quantification in the peripheral blood, which inadequately quantifies their biodistribution and activation status in the tissues. Non-invasive molecular imaging of CAR T cells by positron emission tomograp...

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Publicat a:Clin Cancer Res
Autors principals: Simonetta, Federico, Alam, Israt S., Lohmeyer, Juliane K., Sahaf, Bita, Good, Zinaida, Chen, Weiyu, Xiao, Zunyu, Hirai, Toshihito, Scheller, Lukas, Engels, Pujan, Vermesh, Ophir, Robinson, Elise, Haywood, Tom, Sathirachindra, Ataya, Baker, Jeanette, Malipatlolla, Meena B., Schultz, Liora M., Spiegel, Jay Y., Lee, Jason T., Miklos, David B., Mackall, Crystal L., Gambhir, Sanjiv S., Negrin, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887027/
https://ncbi.nlm.nih.gov/pubmed/33087332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2770
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