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Loop competition and extrusion model predicts CTCF interaction specificity

Three-dimensional chromatin looping interactions play an important role in constraining enhancer–promoter interactions and mediating transcriptional gene regulation. CTCF is thought to play a critical role in the formation of these loops, but the specificity of which CTCF binding events form loops a...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Xi, Wang, Beer, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886907/
https://ncbi.nlm.nih.gov/pubmed/33594051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21368-0
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