A paucigranulocytic asthma host environment promotes the emergence of virulent influenza viral variants

Influenza virus has a high mutation rate, such that within one host different viral variants can emerge. Evidence suggests that influenza virus variants are more prevalent in pregnant and/or obese individuals due to their impaired interferon response. We have recently shown that the non-allergic, pa...

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Veröffentlicht in:eLife
Hauptverfasser: Hulme, Katina D, Karawita, Anjana C, Pegg, Cassandra, Bunte, Myrna JM, Bielefeldt-Ohmann, Helle, Bloxham, Conor J, Van den Hoecke, Silvie, Setoh, Yin Xiang, Vrancken, Bram, Spronken, Monique, Steele, Lauren E, Verzele, Nathalie AJ, Upton, Kyle R, Khromykh, Alexander A, Chew, Keng Yih, Sukkar, Maria, Phipps, Simon, Short, Kirsty R
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2021
Schlagworte:
Immunology and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886327/
https://ncbi.nlm.nih.gov/pubmed/33588989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61803
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