Escherichia coli Nissle 1917 administered as a dextranomar microsphere biofilm enhances immune responses against human rotavirus in a neonatal malnourished pig model colonized with human infant fecal microbiota

Human rotavirus (HRV) is a leading cause of diarrhea in children. It causes significant morbidity and mortality, especially in low- and middle-income countries (LMICs), where HRV vaccine efficacy is low. The probiotic Escherichia coli Nissle (EcN) 1917 has been widely used in the treatment of enteri...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Michael, Husheem, Paim, Francine C., Miyazaki, Ayako, Langel, Stephanie N., Fischer, David D., Chepngeno, Juliet, Goodman, Steven D., Rajashekara, Gireesh, Saif, Linda J., Vlasova, Anastasia Nickolaevna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886176/
https://ncbi.nlm.nih.gov/pubmed/33592026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246193
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