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Optical trapping assisted detection rate enhancement of single molecules on a nanopore optofluidic chip

We use optical trapping to deliver molecular targets to the vicinity of a nanopore for high-throughput single molecule analysis on an optofluidic chip. DNA detection rates increase over 80× to enable detection at attomolar concentrations.

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Foilsithe in:Optica
Main Authors: Rahman, M., Harrington, M., Stott, M. A., Li, Y., Sampad, M. J. N., Yuzvinsky, T. D., Hawkins, A. R., Schmidt, H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885897/
https://ncbi.nlm.nih.gov/pubmed/33598506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/optica.6.001130
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