Low expression of NSD1, NSD2, and NSD3 define a subset of human papillomavirus-positive oral squamous carcinomas with unfavorable prognosis

BACKGROUND: Frequent mutations in the nuclear receptor binding SET domain protein 1 (NSD1) gene have been observed in head and neck squamous cell carcinomas (HNSCC). NSD1 encodes a histone 3 lysine-36 methyltransferase. NSD1 mutations are correlated with improved clinical outcomes and increased sens...

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Publicado en:Infect Agent Cancer
Main Authors: Gameiro, Steven F., Ghasemi, Farhad, Zeng, Peter Y. F., Mundi, Neil, Howlett, Christopher J., Plantinga, Paul, Barrett, John W., Nichols, Anthony C., Mymryk, Joe S.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885607/
https://ncbi.nlm.nih.gov/pubmed/33588906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13027-021-00347-6
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