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Targeting cancer stem cells for reversing therapy resistance: mechanism, signaling, and prospective agents

Cancer stem cells (CSCs) show a self-renewal capacity and differentiation potential that contribute to tumor progression and therapy resistance. However, the underlying processes are still unclear. Elucidation of the key hallmarks and resistance mechanisms of CSCs may help improve patient outcomes a...

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Bibliographic Details
Published in:Signal Transduct Target Ther
Main Authors: Zhou, He-Ming, Zhang, Ji-Gang, Zhang, Xue, Li, Qin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884707/
https://ncbi.nlm.nih.gov/pubmed/33589595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-00430-1
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