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IgA binds to the AD‐2 epitope of glycoprotein B and neutralizes human cytomegalovirus

Human cytomegalovirus (HCMV) is a ubiquitous pathogen that is potentially pathogenic in immunosuppressed individuals and pregnant females during primary infection. The HCMV envelope glycoprotein B (gB) facilitates viral entry into all cell types and induces a potent immune response. AD‐2 epitope is...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Siddiqui, Saima, Hackl, Sarah, Ghoddusi, Hamid, McIntosh, Megan R., Gomes, Ariane C., Ho, Joshua, Reeves, Matthew B., McLean, Gary R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884650/
https://ncbi.nlm.nih.gov/pubmed/33283275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13286
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