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The Role of T Cell Receptor Signaling in the Development of Type 1 Diabetes

T cell receptor (TCR) signaling influences multiple aspects of CD4(+) and CD8(+) T cell immunobiology including thymic development, peripheral homeostasis, effector subset differentiation/function, and memory formation. Additional T cell signaling cues triggered by co-stimulatory molecules and cytok...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Clark, Matthew, Kroger, Charles J., Ke, Qi, Tisch, Roland M.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884625/
https://ncbi.nlm.nih.gov/pubmed/33603744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.615371
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