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Decreased expression of TERT and telomeric proteins as human ovaries age may cause telomere shortening
OBJECTIVE: Telomeres are repetitive sequences localized at the ends of eukaryotic chromosomes comprising noncoding DNA and telomere-binding proteins. TRF1 and TRF2 both bind to the double-stranded telomeric DNA to regulate its length throughout the lifespan of eukaryotic cells. POT1 interacts with s...
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| Udgivet i: | J Assist Reprod Genet |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer US
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7884544/ https://ncbi.nlm.nih.gov/pubmed/32856217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-020-01932-1 |
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