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Decreased expression of TERT and telomeric proteins as human ovaries age may cause telomere shortening

OBJECTIVE: Telomeres are repetitive sequences localized at the ends of eukaryotic chromosomes comprising noncoding DNA and telomere-binding proteins. TRF1 and TRF2 both bind to the double-stranded telomeric DNA to regulate its length throughout the lifespan of eukaryotic cells. POT1 interacts with s...

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Foilsithe in:J Assist Reprod Genet
Main Authors: Uysal, Fatma, Kosebent, Esra Gozde, Toru, Havva Serap, Ozturk, Saffet
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer US 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884544/
https://ncbi.nlm.nih.gov/pubmed/32856217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-020-01932-1
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