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Selective H3 Antagonist (ABT-239) Differentially Modifies Cognitive Function Under the Impact of Restraint Stress

Background: A considerable number of competitive antagonists/inverse agonists of histamine H3 receptor (H3R) have progressed to clinical assessment, with pitolisant approved for the treatment of narcolepsy. H3R, highly expressed in the CNS, is regarded as a relevant target in CNS disorders. At the s...

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Pubblicato in:Front Syst Neurosci
Autori principali: Trofimiuk, Emil, Wielgat, Przemysław, Car, Halina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884464/
https://ncbi.nlm.nih.gov/pubmed/33603652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2020.614810
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