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Structural design principles for specific ultra-high affinity interactions between colicins/pyocins and immunity proteins

The interactions of the antibiotic proteins colicins/pyocins with immunity proteins is a seminal model system for studying protein–protein interactions and specificity. Yet, a precise and quantitative determination of which structural elements and residues determine their binding affinity and specif...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Shushan, Avital, Kosloff, Mickey
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884437/
https://ncbi.nlm.nih.gov/pubmed/33589691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83265-2
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