Glutamine Deprivation Promotes the Generation and Mobilization of MDSCs by Enhancing Expression of G-CSF and GM-CSF

Solid tumors are often challenged by hypoxic and nutrient-deprived tumor microenvironments (TME) as tumors progress, due to limited perfusion and rapid nutrient consumption. While cancer cells can demonstrate the ability to survive in nutrient-deprived conditions through multiple intrinsic alteratio...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Sun, Hong-Wei, Wu, Wen-Chao, Chen, Hai-Tian, Xu, Yi-Tuo, Yang, Yan-Yan, Chen, Jing, Yu, Xing-Juan, Wang, Zilian, Shuang, Ze-Yu, Zheng, Limin
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884351/
https://ncbi.nlm.nih.gov/pubmed/33603745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.616367
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