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Decreased p53 is associated with a decline in asymmetric stem cell self‐renewal in aged human epidermis

With age, the epidermis becomes hypoplastic and hypoproliferative. Hypoproliferation due to aging has been associated with decreased stem cell (SC) self‐renewal in multiple murine tissues. The fate of SC self‐renewal divisions can be asymmetric (one SC, one committed progenitor) or symmetric (two SC...

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Detaylı Bibliyografya
Yayımlandı:Aging Cell
Asıl Yazarlar: Charruyer, Alexandra, Weisenberger, Tracy, Li, Hang, Khalifa, Ayman, Schroeder, Andrew W., Belzer, Annika, Ghadially, Ruby
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884041/
https://ncbi.nlm.nih.gov/pubmed/33524216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13310
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