Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans

Using samples from the New England Centenarian Study (NECS), we sought to characterize the serum proteome of 77 centenarians, 82 centenarians' offspring, and 65 age‐matched controls of the offspring (mean ages: 105, 80, and 79 years). We identified 1312 proteins that significantly differ betwee...

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Vydáno v:Aging Cell
Hlavní autoři: Sebastiani, Paola, Federico, Anthony, Morris, Melody, Gurinovich, Anastasia, Tanaka, Toshiko, Chandler, Kevin B., Andersen, Stacy L., Denis, Gerald, Costello, Catherine E., Ferrucci, Luigi, Jennings, Lori, Glass, David J., Monti, Stefano, Perls, Thomas T.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884029/
https://ncbi.nlm.nih.gov/pubmed/33512769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13290
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