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Confirming and expanding the phenotypes of FZD5 variants: Coloboma, inferior chorioretinal hypoplasia, and high myopia

PURPOSE: Two frameshift and two indel variants in FZD5 have been reported to cause coloboma in two families with incomplete penetrance and in two isolated cases in previous studies, respectively. This study aims to confirm this association and expand related specific phenotypes based on the genotype...

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Publicat a:Mol Vis
Autors principals: Jiang, Yi, Ouyang, Jiamin, Li, Shiqiang, Xiao, Xueshan, Sun, Wenmin, Zhang, Qingjiong
Format: Artigo
Idioma:Inglês
Publicat: Molecular Vision 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883931/
https://ncbi.nlm.nih.gov/pubmed/33633439
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