A Delta-Opioid Receptor Gene Polymorphism Moderates the Therapeutic Response to Extended-Release Buprenorphine in Opioid Use Disorder

BACKGROUND: Buprenorphine treatment is not equally effective in all patients with opioid use disorder (OUD). Two retrospective studies showed that, among African Americans (AAs), rs678849, a polymorphism in the delta-opioid receptor gene, moderated the therapeutic effect of sublingual buprenorphine....

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Kranzler, Henry R, Lynch, Kevin G, Crist, Richard C, Hartwell, Emily, Le Moigne, Anne, Laffont, Celine M, Andorn, Anne C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Regular Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883889/
https://ncbi.nlm.nih.gov/pubmed/32920647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyaa069
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