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Quantitative systems pharmacology model predictions for efficacy of atezolizumab and nab-paclitaxel in triple-negative breast cancer

BACKGROUND: Immune checkpoint blockade therapy has clearly shown clinical activity in patients with triple-negative breast cancer, but less than half of the patients benefit from the treatments. While a number of ongoing clinical trials are investigating different combinations of checkpoint inhibito...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Wang, Hanwen, Ma, Huilin, Sové, Richard J, Emens, Leisha A, Popel, Aleksander S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883871/
https://ncbi.nlm.nih.gov/pubmed/33579739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002100
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