Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis

SUMMARY: Aiming to identify pleiotropic genomic loci for bone mineral density and bone size, we performed a bivariate GWAS in five discovery samples and replicated in two large-scale samples. We identified 2 novel loci at 2q37.1 and 6q26. Our findings provide insight into common genetic architecture...

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Publicat a:Osteoporos Int
Autors principals: Zhang, H., Liu, L., Ni, J.-J., Wei, X.-T., Feng, G.-J., Yang, X.-L., Xu, Q., Zhang, Z.-J., Hai, R., Tian, Q., Shen, H., Deng, H.-W., Pei, Y.-F., Zhang, L.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883523/
https://ncbi.nlm.nih.gov/pubmed/32314116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00198-020-05389-x
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