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Steroid‐dependent switch of OvoL/Shavenbaby controls self‐renewal versus differentiation of intestinal stem cells

Adult stem cells must continuously fine‐tune their behavior to regenerate damaged organs and avoid tumors. While several signaling pathways are well known to regulate somatic stem cells, the underlying mechanisms remain largely unexplored. Here, we demonstrate a cell‐intrinsic role for the OvoL fami...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Al Hayek, Sandy, Alsawadi, Ahmad, Kambris, Zakaria, Boquete, Jean‐Philippe, Bohère, Jérôme, Immarigeon, Clément, Ronsin, Brice, Plaza, Serge, Lemaitre, Bruno, Payre, François, Osman, Dani
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883054/
https://ncbi.nlm.nih.gov/pubmed/33372708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019104347
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