Carveol a Naturally-Derived Potent and Emerging Nrf2 Activator Protects Against Acetaminophen-Induced Hepatotoxicity

Acetaminophen (N-acetyl p-aminophenol or APAP) is used worldwide for its antipyretic and anti-inflammatory potential. However, APAP overdose sometimes causes severe liver damage. In this study, we elucidated the protective effects of carveol in liver injury, using molecular and in silico approaches....

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Rahman, Zaif Ur, Al Kury, Lina Tariq, Alattar, Abdullah, Tan, Zhen, Alshaman, Reem, Malik, Imran, Badshah, Haroon, Uddin, Zia, Khan Khalil, Atif Ali, Muhammad, Naveed, Khan, Saifullah, Ali, Amjad, Shah, Fawad Ali, Li, Jing Bo, Li, Shupeng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883019/
https://ncbi.nlm.nih.gov/pubmed/33597885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.621538
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