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Metformin alleviates allergic airway inflammation and increases Treg cells in obese asthma

Obesity increases the morbidity and severity of asthma, with poor sensitivity to corticosteroid treatment. Metformin has potential effects on improving asthma airway inflammation. Regulatory T cells (Tregs) play a key role in suppressing the immunoreaction to allergens. We built an obese asthmatic m...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Guo, Yimin, Shi, Jianting, Wang, Qiujie, Hong, Luna, Chen, Ming, Liu, Shanying, Yuan, Xiaoqing, Jiang, Shanping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7882927/
https://ncbi.nlm.nih.gov/pubmed/33421348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16269
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