Characterisation of cough evoked by inhaled treprostinil and treprostinil palmitil

Cough is induced by inhaled prostacyclin analogues including treprostinil (TRE), and, at higher doses, treprostinil palmitil (TP), a prodrug of TRE. In this report, we have investigated mechanisms involved in TRE- and TP-induced cough, using a dry powder formulation of TP (TPIP) to supplement previo...

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Vydáno v:ERJ Open Res
Hlavní autoři: Chapman, Richard W., Corboz, Michel R., Fernandez, Carlos, Sullivan, Eugene, Stautberg, Andy, Plaunt, Adam J., Konicek, Donna M., Malinin, Vladimir, Li, Zhili, Cipolla, David, Perkins, Walter
Médium: Artigo
Jazyk:Inglês
Vydáno: European Respiratory Society 2021
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7882781/
https://ncbi.nlm.nih.gov/pubmed/33614774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00592-2020
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