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Interleukin-33 Amplifies Human Mast Cell Activities Induced by Complement Anaphylatoxins

Both, aberrant mast cell responses and complement activation contribute to allergic diseases. Since mast cells are highly responsive to C3a and C5a, while Interleukin-33 (IL-33) is a potent mast cell activator, we hypothesized that IL-33 critically regulates mast cell responses to complement anaphyl...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: West, Peter W., Bahri, Rajia, Garcia-Rodriguez, Karen M., Sweetland, Georgia, Wileman, Georgia, Shah, Rajesh, Montero, Angeles, Rapley, Laura, Bulfone-Paus, Silvia
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7882629/
https://ncbi.nlm.nih.gov/pubmed/33597949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.615236
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