CD8(+)CD161(+) T-Cells: Cytotoxic Memory Cells With High Therapeutic Potential

NK1.1 and its human homolog CD161 are expressed on NK cells, subsets of CD4(+) and CD8(+) T cells, and NKT cells. While the expression of NK1.1 is thought to be inhibitory to NK cell function, it is reported to play both costimulatory and coinhibitory roles in T-cells. CD161 has been extensively stu...

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Foilsithe in:Front Immunol
Main Authors: Konduri, Vanaja, Oyewole-Said, Damilola, Vazquez-Perez, Jonathan, Weldon, Scott A., Halpert, Matthew M., Levitt, Jonathan M., Decker, William K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Immunology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7882609/
https://ncbi.nlm.nih.gov/pubmed/33597948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.613204
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