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A web tool for the design of prime-editing guide RNAs

Prime editing enables diverse genomic alterations to be written into target sites without requiring double-strand breaks or donor templates. The design of prime-editing guide RNAs (pegRNAs), which must be customized for each edit, can however be complex and time-consuming. Compared with single guide...

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書目詳細資料
發表在:Nat Biomed Eng
Main Authors: Chow, Ryan D., Chen, Jennifer S., Shen, Johanna, Chen, Sidi
格式: Artigo
語言:Inglês
出版: 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7882013/
https://ncbi.nlm.nih.gov/pubmed/32989284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-020-00622-8
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