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Enhanced Ca(2+) influx in mechanically distorted erythrocytes measured with (19)F nuclear magnetic resonance spectroscopy

We present the first direct nuclear magnetic resonance (NMR) evidence of enhanced entry of Ca(2+) ions into human erythrocytes (red blood cells; RBCs), when these cells are mechanically distorted. For this we loaded the RBCs with the fluorinated Ca(2+) chelator, 1,2-bis(2-amino-5-fluorophenoxy)ethan...

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Publicat a:Sci Rep
Autors principals: Kuchel, Philip W., Romanenko, Konstantin, Shishmarev, Dmitry, Galvosas, Petrik, Cox, Charles D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881017/
https://ncbi.nlm.nih.gov/pubmed/33580124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83044-z
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