Histone variant H2A.B-H2B dimers are spontaneously exchanged with canonical H2A-H2B in the nucleosome

H2A.B is an evolutionarily distant histone H2A variant that accumulates on DNA repair sites, DNA replication sites, and actively transcribing regions in genomes. In cells, H2A.B exchanges rapidly in chromatin, but the mechanism has remained enigmatic. In the present study, we found that the H2A.B-H2...

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Udgivet i:Commun Biol
Main Authors: Hirano, Rina, Arimura, Yasuhiro, Kujirai, Tomoya, Shibata, Mikihiro, Okuda, Aya, Morishima, Ken, Inoue, Rintaro, Sugiyama, Masaaki, Kurumizaka, Hitoshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881002/
https://ncbi.nlm.nih.gov/pubmed/33580188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01707-z
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