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Effect of microdistribution of alpha and beta-emitters in targeted radionuclide therapies on delivered absorbed dose in a GATE model of bone marrow

Acute hematologic toxicity is a frequent adverse effect of beta-emitter targeted radionuclide therapies (TRTs). Alpha emitters have the potential of delivering high linear energy transfer (LET) radiation to the tumor attributed to its shorter range. Antibody-based TRTs have increased blood-pool half...

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Veröffentlicht in:Phys Med Biol
Hauptverfasser: Tranel, Jonathan, Feng, Felix Y., St. James, Sara, Hope, Thomas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880907/
https://ncbi.nlm.nih.gov/pubmed/33321484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1361-6560/abd3ef
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