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Tissue-autonomous immune response regulates stress signaling during hypertrophy

Postmitotic tissues are incapable of replacing damaged cells through proliferation, but need to rely on buffering mechanisms to prevent tissue disintegration. By constitutively activating the Ras/MAPK-pathway via Ras(V12)-overexpression in the postmitotic salivary glands (SGs) of Drosophila larvae,...

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Bibliographic Details
Published in:eLife
Main Authors: Krautz, Robert, Khalili, Dilan, Theopold, Ulrich
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880693/
https://ncbi.nlm.nih.gov/pubmed/33377870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64919
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