Curcumin promotes AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPARα signaling pathway

Curcumin is a polyphenol compound that exhibits multiple physiological activities. To elucidate the mechanisms by which curcumin affects systemic amyloidosis, we investigated amyloid deposition and molecular changes in a mouse model of amyloid apolipoprotein A-II (AApoAII) amyloidosis, in which mice...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Dai, Jian, Li, Ying, Kametani, Fuyuki, Cui, Xiaoran, Igarashi, Yuichi, Huo, Jia, Miyahara, Hiroki, Mori, Masayuki, Higuchi, Keiichi
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2021
Assuntos:
Biochemistry and Chemical Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880682/
https://ncbi.nlm.nih.gov/pubmed/33496266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63538
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