Alzheimer’s disease brain-derived extracellular vesicles spread tau pathology in interneurons

Extracellular vesicles are highly transmissible and play critical roles in the propagation of tau pathology, although the underlying mechanism remains elusive. Here, for the first time, we comprehensively characterized the physicochemical structure and pathogenic function of human brain-derived extr...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Ruan, Zhi, Pathak, Dhruba, Venkatesan Kalavai, Srinidhi, Yoshii-Kitahara, Asuka, Muraoka, Satoshi, Bhatt, Nemil, Takamatsu-Yukawa, Kayo, Hu, Jianqiao, Wang, Yuzhi, Hersh, Samuel, Ericsson, Maria, Gorantla, Santhi, Gendelman, Howard E, Kayed, Rakez, Ikezu, Seiko, Luebke, Jennifer I, Ikezu, Tsuneya
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880668/
https://ncbi.nlm.nih.gov/pubmed/33246331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awaa376
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