Low DAPK1 expression correlates with poor prognosis and sunitinib resistance in clear cell renal cell carcinoma

We investigated the prognostic significance of Death-Associated Protein Kinase 1 (DAPK1) and its role in sunitinib resistance in clear cell renal cell carcinoma (ccRCC). DAPK1 mRNA levels were significantly lower in tumor tissues than normal kidney tissues in TCGA-KIRC dataset (n=428). Both overall...

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Detalles Bibliográficos
Publicado en:Aging (Albany NY)
Autores principales: Song, Zhengshuai, Li, Zhongyuan, Han, Weiwei, Zhu, Chenxi, Lou, Ning, Li, Xuechao, Luo, Gang, Peng, Song, Li, Guohao, Zhao, Ye, Guo, Yonglian
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880360/
https://ncbi.nlm.nih.gov/pubmed/33201837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103638
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