Excessive fibroblast growth factor 23 promotes renal fibrosis in mice with type 2 cardiorenal syndrome

Cardiorenal syndrome (CRS) has a high mortality, but its pathogenesis remains elusive. Fibroblast growth factor 23 (FGF23) is increased in both renal dysfunction and cardiac dysfunction, and FGF receptor 4 (FGFR4) has been identified as a receptor for FGF23. Deficiency of FGF23 causes growth retarda...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Hao, Huixin, Ma, Siyuan, Zheng, Cankun, Wang, Qiancheng, Lin, Hairuo, Chen, Zhenhuan, Xie, Jiahe, Chen, Lin, Chen, Kaitong, Wang, Yuegang, Huang, Xiaobo, Cao, Shiping, Liao, Wangjun, Bin, Jianping, Liao, Yulin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7880350/
https://ncbi.nlm.nih.gov/pubmed/33460402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202448
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