Solasonine Suppresses the Proliferation of Acute Monocytic Leukemia Through the Activation of the AMPK/FOXO3A Axis

Solasonine, the main active ingredient of Solanum nigrum L., has been reported to exert extensive antitumor activity. However, the antitumor effects in acute monocytic leukemia and the exact mechanisms involved are unknown. In this study, we investigated the role of solasonine on inhibiting the prog...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Zhang, Hong, Tian, Fang, Jiang, Pengjun, Qian, Shushu, Dai, Xingbin, Ma, Bangyun, Wang, Mengya, Dai, Huibo, Sha, Xiaocao, Yang, Zhongfa, Zhu, Xuejun, Sun, Xuemei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879981/
https://ncbi.nlm.nih.gov/pubmed/33585239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.614067
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