Solasonine Suppresses the Proliferation of Acute Monocytic Leukemia Through the Activation of the AMPK/FOXO3A Axis

Solasonine, the main active ingredient of Solanum nigrum L., has been reported to exert extensive antitumor activity. However, the antitumor effects in acute monocytic leukemia and the exact mechanisms involved are unknown. In this study, we investigated the role of solasonine on inhibiting the prog...

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Veröffentlicht in:Front Oncol
Hauptverfasser: Zhang, Hong, Tian, Fang, Jiang, Pengjun, Qian, Shushu, Dai, Xingbin, Ma, Bangyun, Wang, Mengya, Dai, Huibo, Sha, Xiaocao, Yang, Zhongfa, Zhu, Xuejun, Sun, Xuemei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879981/
https://ncbi.nlm.nih.gov/pubmed/33585239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.614067
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