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Polytherapeutic strategies with oncolytic virus–bortezomib and adjuvant NK cells in cancer treatment

Proteasome inhibition and oncolytic virotherapy are two emerging targeted cancer therapies. Bortezomib, a proteasome inhibitor, disrupts the degradation of proteins in the cell leading to accumulation of unfolded proteins inducing apoptosis. On the other hand, oncolytic virotherapy uses genetically...

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Pubblicato in:J R Soc Interface
Autori principali: Aspirin, Angelica P., de los Reyes V, Aurelio A., Kim, Yangjin
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879760/
https://ncbi.nlm.nih.gov/pubmed/33402021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0669
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