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Yolk sac, but not hematopoietic stem cell–derived progenitors, sustain erythropoiesis throughout murine embryonic life

In the embryo, the first hematopoietic cells derive from the yolk sac and are thought to be rapidly replaced by the progeny of hematopoietic stem cells. We used three lineage-tracing mouse models to show that, contrary to what was previously assumed, hematopoietic stem cells do not contribute signif...

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Detalles Bibliográficos
Publicado en:J Exp Med
Autores principales: Soares-da-Silva, Francisca, Freyer, Laina, Elsaid, Ramy, Burlen-Defranoux, Odile, Iturri, Lorea, Sismeiro, Odile, Pinto-do-Ó, Perpétua, Gomez-Perdiguero, Elisa, Cumano, Ana
Formato: Artigo
Lenguaje:Inglês
Publicado: Rockefeller University Press 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879581/
https://ncbi.nlm.nih.gov/pubmed/33566111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201729
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