Lycorine inhibits cell proliferation, migration and invasion, and primarily exerts in vitro cytostatic effects in human colorectal cancer via activating the ROS/p38 and AKT signaling pathways

Colorectal cancer (CRC) is a life-threatening malignant tumor of the digestive tract. Diverse gene mutations and complicated alterations to the signaling pathways in CRC lead to heterogeneity in response to chemotherapy. Moreover, anticancer drugs for CRC chemotherapy are limited due to adverse even...

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Veröffentlicht in:Oncol Rep
Hauptverfasser: Zhang, Ping, Yuan, Xiaohui, Yu, Tingting, Huang, Huakun, Yang, Chunmei, Zhang, Lulu, Yang, Shengdong, Luo, Xiaoji, Luo, Jinyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2021
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7879421/
https://ncbi.nlm.nih.gov/pubmed/33649853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2021.7970
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